This is a complex issue with the number of vaccinations now available for our dogs and cats. The core vaccines for dogs are distemper, parvo, and rabies. Whle the core for cats are panleukopenia, rhinotracheitis, and rabies The simple answer is that puppies and kittens should receive a series of at least 2 vaccinations, culminating at 16 weeks along with a rabies vaccine. They should get a booster a year later. Then get boosters every 3 years. Now there are a plethora of special vaccines that have their own requirements. Some are required by geography, such as Lyme’s Disease, while others are special circumstances, such as Kennel Cough. The frequency and need of these vaccines should be discussed with your veterinarian.